Baker lab

Publications

2021

GEVI cell‐type specific labelling and a manifold learning approach provide evidence for lateral inhibition at the population level in the mouse hippocampal CA1 area

R Nakajima, N Laskaris, JK Rhee, BJ Baker, EK Kosmidis

European Journal of Neuroscience

2020

Biophysical Parameters of GEVIs: Considerations for Imaging Voltage

JK Rhee, LM Leong, MSI Mukim, BE Kang, S Lee, L Bilbao-Broch, BJ Baker

Biophysical Journal 119 (1), 1-8

2020

Proton wires mediate the optical signal for ArcLight-type Genetically Encoded Voltage Indicators

BE Kang, LM Leong, Y Kim, K Miyazaki, WN Ross, BJ Baker

2020

Conserved amino acids residing outside the voltage field can shift the voltage sensitivity and increase the signal size of Ciona based GEVIs

M Sepehri-Rad, LB Cohen, BJ Baker

2020

Improving the flexibility of Genetically Encoded Voltage Indicators via intermolecular FRET

LM Leong, BE Kang, BJ Baker

2019

Engineering Photoactivatability in Genetically Encoded Voltage and pH Indicators

S Lee, YK Song, BJ Baker

Frontiers in Cellular Neuroscience 13, 482

2019

Development of Photoactivatable Optical Bio-Sensors of Physiological Activities

S Lee, YK Song, BJ Baker

Biophysical Journal 116 (3), 149a

Optical consequences of a genetically-encoded voltage indicator with a pH sensitive fluorescent protein

BE Kang, S Lee, BJ Baker

Neuroscience Research 146, 13-21

2018

Mapping of excitatory and inhibitory postsynaptic potentials of neuronal populations in hippocampal slices using the GEVI, ArcLight

R Nakajima, BJ Baker

Journal of physics D: Applied physics 51 (50), 504003

2018

Monitoring voltage fluctuations of intracellular membranes

M Sepehri-Rad, LB Cohen, O Braubach, BJ Baker

Scientific reports 8 (1), 6911

2018

A dimeric fluorescent protein yields a bright, red-shifted GEVI capable of population signals in brain slice

B Yi, BE Kang, S Lee, S Braubach, BJ Baker

Scientific reports 8, 15199

2017

Voltage and calcium imaging of brain activity

M Sepehri-Rad, Y Choi, LB Cohen, BJ Baker, S Zhong, DA Storace, OR Braubach

Biophysical journal 113 (10), 2160-2167

2017

Modulating the Voltage-sensitivity of a Genetically Encoded Voltage Indicator

A Jung, D Rajakumar, BJ Yoon, BJ Baker

Experimental neurobiology 26 (5), 241-251

2017

Improving a genetically encoded voltage indicator by modifying the cytoplasmic charge composition

S Lee, T Geiller, A Jung, R Nakajima, YK Song, BJ Baker

Scientific reports 7 (1), 8286

Optogenetic Monitoring of Synaptic Activity with Genetically Encoded Voltage Indicators

R Nakajima, A Jung, BJ Yoon, BJ Baker

Frontiers in Synaptic Neuroscience 8, 22

2016

Imaging voltage in zebrafish as a route to characterizing a vertebrate functional connectome: promises and pitfalls of genetically encoded indicators

S Jesuthasan, C Kibat, S Krishnan, BJ Baker, M Ramaswamy

Journal of Neurogenetics 30 (2), 80-88

2016

Toward Better Genetically Encoded Sensors of Membrane Potential

BJ Baker, D Storace, M Sepehri-Rad, BE Kang, LB Cohen, T Hughes

Trends in Neurosciences 39 (5), 277-89

2016

Pado, a fluorescent protein with proton channel activity can optically monitor membrane potential, intracellular pH, and map gap junctions

BE Kang, BJ Baker

Scientific Reports 6, 23865

2016

Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors

S Lee, HH Piao, M Sepheri-Rad, A Jung, U Sung, YK Song, BJ Baker

J. Vis. Exp. (108), e53566

2015

Developing fast fluorescent protein voltage sensors by optimizing FRET interactions

U Sung, M Sepehri-Rad, HH Piao, L Jin, T Hughes, LB Cohen, BJ Baker

PLoS One 10 (11), e0141585

2015

Linker length and fusion site composition improve the optical signal of genetically encoded fluorescent voltage sensors

A Jung, JE Garcia, E Kim, BJ Yoon, BJ Baker

Neurophotonics 2 (2), 021012

2015

Combinatorial mutagenesis of the voltage-sensing domain enables the optical resolution of action potentials firing at 60 Hz by a genetically encoded fluorescent sensor of membrane potential

HH Piao, D Rajakumar, BE Kang, EH Kim, BJ Baker

Journal of Neuroscience 35 (1), 372-385

2015

Genetically encoded protein sensors of membrane potential

D Storace, MS Rad, Z Han, L Jin, LB Cohen, T Hughes, BJ Baker, U Sung

Membrane Potential Imaging in the Nervous System and Heart, 493-509

2013

Fluorescent protein voltage probes derived from ArcLight that respond to membrane voltage changes with fast kinetics

Z Han, L Jin, J Platisa, LB Cohen, BJ Baker, VA Pieribone

PloS one 8 (11), e81295

Genetically encoded fluorescent voltage sensors using the voltage-sensing domain of Nematostella and Danio phosphatases exhibit fast kinetics

BJ Baker, L Jin, Z Han, LB Cohen, M Popovic, J Platisa, V Pieribone

Journal of neuroscience methods 208 (2), 190-196

2012

Random insertion of split-cans of the fluorescent protein venus into Shaker channels yields voltage sensitive probes with improved membrane localization in mammalian cells

L Jin, B Baker, R Mealer, L Cohen, V Pieribone, A Pralle, T Hughes

Journal of neuroscience methods 199 (1), 1-9

2011

Genetically encoded protein sensors of membrane potential

L Jin, H Mutoh, T Knopfel, LB Cohen, T Hughes, VA Pieribone, EY Isacoff, BM Salzberg, BJ Baker

Membrane potential imaging in the nervous system, 157-163

2010

Fluorescent Sensors of Membrane Potential that Are Genetically Encoded

L Jin, BJ Baker, LB Cohen, H Mutoh, D Dimitrov, A Perron, Y Iwamoto, EY Isacoff, VA Pieribone, T Hughes, T Knöpfel, W Akemann

Imaging the Brain with Optical Methods, 27-43

2009

Wide-field and two-photon imaging of brain activity with voltage and calcium-sensitive dyes

R Homma, BJ Baker, L Jin, O Garaschuk, A Konnerth, LB Cohen, CX Bleau, M Canepari, M Djurisic, D Zecevic

Dynamic Brain Imaging, 43-79

2008

Genetically encoded fluorescent sensors of membrane potential

BJ Baker, H Mutoh, D Dimitrov, W Akemann, A Perron, Y Iwamoto, L Jin, LB Cohen, EY Isacoff, VA Pieribone, T Hughes, T Knöpfel

Brain cell biology 36 (1-4), 53

2007

Engineering and characterization of an enhanced fluorescent protein voltage sensor

D Dimitrov, Y He, H Mutoh, BJ Baker, L Cohen, W Akemann, T Knöpfel

PloS one 2 (5), e440

2007

Three fluorescent protein voltage sensors exhibit low plasma membrane expression in mammalian cells

BJ Baker, H Lee, VA Pieribone, LB Cohen, EY Isacoff, T Knöpfel, EK Kosmidis

Journal of neuroscience methods 161 (1), 32-38

Imaging brain activity with voltage-and calcium-sensitive dyes

BJ Baker, EK Kosmidis, D Vucinic, CX Falk, LB Cohen, M Djurisic, D Zecevic

Cellular and molecular neurobiology 25 (2), 245-282

2005

The evolutionarily related major histocompatibility complex and CD1: evolution of an endogenous retrovirus responsible for a polymorphism in human C4 and the biochemical characterizations of CD1A and E

BJ Baker

The Ohio State University

1998

Demonstration of Human Leukocyte Differentiation Antigen CD1e

B Baker, A Mendoza, C Daniels, A Parker, R Pannell, C Milstein, C Yu

The Journal of Allergy and Clinical Immunology 99 (1), 114

1997

Complement component C4 gene intron 9 as a phylogenetic marker for primates: long terminal repeats of the endogenous retrovirus ERV-K (C4) are a molecular clock of evolution

AW Dangel, BJ Baker, AR Mendoza, CY Yu

Immunogenetics 42 (1), 41-52

1995

The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates

AW Dangel, AR Mendoza, CD Menachery, BJ Baker, CM Daniel, MC Carroll, LC Wu, CY Yu

Immunogenetics 40 (6), 425-436

1994

Deacetoxycephalosporin C hydroxylase of Streptomyces clavuligerus. Purification, characterization, bifunctionality, and evolutionary implication.

WK Yeh, BJ Baker, JE Dotzlaf

J Biol Chem., 5087-93

1991